BOTOX®

The Allergan brand of Botulinum toxin A. This is currently the only FDA approved botulinum toxin A on the US market. BOTOX® comes in a small 100 unit vial. The vial contains approximately 500 nanograms of purified protein. The product is dry in the vial and is reconstituted in the doctor’s office with saline. How much saline is used determines how many units of BOTOX® are in the 1 cc syringe. Typical dilutions vary between 2 to 4 ml. A 2 ml dilution produces a 1 cc syringe that contains 50 units of BOTOX®. A 4 ml dilution produces a 1 cc syringe that contains 25 units of BOTOX®. Be aware that some office dilute their BOTOX® with as much as 20 ml of saline producing a syringe that contains just 5 units of BOTOX®. There are two other Botulinum toxin A products that are pending FDA approval including Reloxin® and Puretox®.

Glossary